Sarcopenia Associated with Insulin Resistance

It has been hypothesized that sarcopenia, a condition where low skeletal muscle mass and strength are present, puts individuals at risk for developing Type 2 diabetes.

To gauge the effect of sarcopenia on insulin resistance and blood glucose levels in both obese and non-obese people, UCLA researchers performed a cross-sectional analysis of data on 14,528 people from the National Health and Nutrition Examination Survey III.

They found that sarcopenia was associated with insulin resistance in both obese and non-obese individuals. It was also associated with high blood-sugar levels in obese people but not in thin people. These associations were stronger in people under age 60 years, in whom sarcopenia was associated with high levels of blood sugar in both obese and thin people, and with diabetes in obese individuals.

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